BDBM293028 1-[6-(6-methyl-1H-indazol-3-yl)-2,3-dihydroindol-1-yl]prop-2-en-1-one ::US20260015351, Compound 4

SMILES C=CC(=O)N1CCc2ccc(-c3n[nH]c4cc(C)ccc34)cc21

InChI Key InChIKey=QXENSQHGDNWATJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 293028   

TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Axonis Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 293028BDBM293028(1-[6-(6-methyl-1H-indazol-3-yl)-2,3-dihydroindol-1...)
Affinity DataKd:  7.80nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details
US Patent

TargetDual specificity mitogen-activated protein kinase kinase 7(Human)
Axonis Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 293028BDBM293028(1-[6-(6-methyl-1H-indazol-3-yl)-2,3-dihydroindol-1...)
Affinity DataIC50: 23nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2026
Entry Details
US Patent