BDBM312689 US9604998, Example 88
SMILES C[C@H]1Cc2cc(CCN3CCN4C[C@H](OC[C@@H]4C3)c3ccc(F)c([N+]#[C-])c3C)ccc2C(=O)O1
InChI Key InChIKey=BMYXPAZBQACECJ-ADSMNUKGSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 312689
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 50nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair