BDBM312689 US9604998, Example 88

SMILES C[C@H]1Cc2cc(CCN3CCN4C[C@H](OC[C@@H]4C3)c3ccc(F)c([N+]#[C-])c3C)ccc2C(=O)O1

InChI Key InChIKey=BMYXPAZBQACECJ-ADSMNUKGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312689   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312689(US9604998, Example 88)
Affinity DataIC50:  50nMAssay Description:Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent