BDBM313766 US10167285, Example 11

SMILES Fc1ncc2NC(Cc3c4Oc4ccc3I)N(CCCC#C)c2n1

InChI Key InChIKey=XWSKWAZLZAXSEN-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313766   

TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313766(US10167285, Example 11)
Affinity DataEC50:  22.3nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313766(US10167285, Example 11)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313766(US10167285, Example 11)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent