BDBM313770 US10167285, Comp 2

SMILES COc1cc(Cl)c(SC2Nc3cnc(F)nc3N2CCCC#C)c(OC)c1OC

InChI Key InChIKey=GJJDKQZSNLNREF-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 313770   

TargetHeat shock protein HSP 90-alpha(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313770(US10167285, Comp 2)
Affinity DataEC50:  120nMAssay Description:The biochemical assay tests competitive binding of compounds to recombinant Hsp90α protein and also Hsp90 found in cell specific complexes, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313770(US10167285, Comp 2)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Memorial Sloan-Kettering Cancer Center

US Patent
LigandPNGBDBM313770(US10167285, Comp 2)
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent