BDBM319535 N-[(cyclopropyl- carbamoyl) methyl]-2-(4- fluorobenzene- sulfonyl)-2-[6-(2- hydroxypyridin- 4-yl)-1,3- benzothiazol-2- yl]acetamide::US10173991, Example 599

SMILES Oc1cc(ccn1)-c1ccc2nc(sc2c1)C(C(=O)NCC(=O)NC1CC1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=GUHRLFXUQDEIBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319535   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319535(N-[(cyclopropyl- carbamoyl) methyl]-2-(4- fluorobe...)
Affinity DataIC50: 27nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent