BDBM327902 5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4-(4- methylpiperazin-1- yl)phenyl)picolinamide::US10377742, Compound 41::US9663496, Compound 41

SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc(cn2)C(=O)N2CCN(Cc3ccc(F)cc3)CC2)cc1

InChI Key InChIKey=QSOJIZDCHOEGLA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327902   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327902(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327902(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-N-(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2020
Entry Details
US Patent