BDBM3500 3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(4-methylpiperazin-1-yl)propyl]amino}pyrido[2,3-d]pyrimidin-7-yl]thiourea::6-arylpyrido[2,3-d]pyrimidine deriv. 82

SMILES CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(NC(=S)NC(C)(C)C)nc3n2)CC1

InChI Key InChIKey=CTVVRRLXHQIPMG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3500   

LigandChemical structure of BindingDB Monomer ID 3500BDBM3500(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(4-me...)
Affinity DataIC50: 100nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3500BDBM3500(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(4-me...)
Affinity DataIC50: 220nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 3500BDBM3500(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[3-(4-me...)
Affinity DataIC50: 1.90E+3nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2005
Entry Details Article
PubMed