BDBM3508 6-methoxy-N-phenylquinazolin-4-amine::CHEMBL328879::PD153035 Analog 7

SMILES COc1ccc2ncnc(Nc3ccccc3)c2c1

InChI Key InChIKey=GKRKTKNUATZSTP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3508   

TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3508(CHEMBL328879 | 6-methoxy-N-phenylquinazolin-4-amin...)
Affinity DataIC50: 55nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3508(CHEMBL328879 | 6-methoxy-N-phenylquinazolin-4-amin...)
Affinity DataIC50: 56nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM3508(CHEMBL328879 | 6-methoxy-N-phenylquinazolin-4-amin...)
Affinity DataIC50: 120nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed