BDBM354700 Preparation of ((2R,5S)-3-(3-trifluoromethyl-4-nitrophenyl)-2-(trifluoromethyl)oxazolidin-5-yl)methanol::US9809583, Example 8

SMILES [O-][N+](=O)c1ccc(OC[C@@H]2CN([C@H](O2)C(F)(F)F)c2ccc(C#N)c(c2)C(F)(F)F)cc1

InChI Key InChIKey=YJNBVACVQFKVGK-DOTOQJQBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 354700   

TargetAndrogen receptor(Chlorocebus sabaeus (Green monkey) (Cercopithecus ...)
Dong-A St

US Patent
LigandPNGBDBM354700(Preparation of ((2R,5S)-3-(3-trifluoromethyl-4-nit...)
Affinity DataIC50:  13.7nMAssay Description:In order to examine binding ability of the agonists of the present invention to androgen receptors, the following in-vitro experiment was performed. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent