BDBM360542 2-(3-bromophenyl)-N-((5-(3- methoxyphenyl)isoquinolin-8- yl)methyl)cyclopropanecarboxamide::US9828369, Example 99

SMILES COc1cccc(c1)-c1ccc(CNC(=O)C2CC2c2ccc(Br)cc2)c2cnccc12

InChI Key InChIKey=CHSVODNHYBUQCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 360542   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharpe & Dohme

US Patent
LigandPNGBDBM360542(2-(3-bromophenyl)-N-((5-(3- methoxyphenyl)isoquino...)
Affinity DataIC50:  230nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent