BDBM370378 Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropylphenyl)(1-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-4-yl)methyl) carbamoyl)cyclopentane-1-carboxylic acid ::US20260021085, Compound 7

SMILES CC(C)c1ccc([C@@H](NC(=O)[C@@H]2CCC[C@@H]2C(=O)O)c2cccc3c2[nH]c(=O)n3C)cc1F

InChI Key InChIKey=UQGBFFRGAROTJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370378   

TargetGlycogen [starch] synthase, muscle/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 370378BDBM370378(Synthesis of (1S,2R)-2-(((R)-(3-fluoro-4-isopropyl...)
Affinity DataIC50: 884nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent