BDBM372263 US20260021085, Compound 11

SMILES CC(C)c1ccc([C@@H](NC(=O)C2CC(NC(=O)OC(C)(C)C)CC2C(=O)O)c2ccccc2)cc1

InChI Key InChIKey=UWTDBQIXEHMZAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 372263   

TargetGlycogen [starch] synthase, muscle/Glycogenin-1 (GN1)(Human)
Maze Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 372263BDBM372263(US20260021085, Compound 11)
Affinity DataIC50: 1.95E+3nMAssay Description:Compounds that inhibit the hGYS1 enzyme and, subsequently, the downstream conversion of NADH to NAD+, were tested using assay ready plates (black, cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent