BDBM373226 US20260022122, Example 17

SMILES O=C(NCc1ccc(-c2nc3ccc(F)cc3o2)cc1)c1cnc2nccn2c1

InChI Key InChIKey=OJUSLJYLBQWGAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373226   

TargetNicotinamide phosphoribosyltransferase(Human)
Checkmate Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 373226BDBM373226(US20260022122, Example 17)
Affinity DataIC50: 75nMAssay Description:To test the effect of the compound prepared in each Example on the substrate decomposition rate (Vmax/min) mediated by NamPT enzyme, IC50 was calcula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent