BDBM373281 US20260022122, Example 52

SMILES COc1ccc2nc(-c3ccc(CNC(=O)c4cnc5nccn5c4)cc3)sc2c1

InChI Key InChIKey=MRAWQEBCLHSDGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373281   

TargetNicotinamide phosphoribosyltransferase(Human)
Checkmate Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 373281BDBM373281(US20260022122, Example 52)
Affinity DataIC50: 50nMAssay Description:To test the effect of the compound prepared in each Example on the substrate decomposition rate (Vmax/min) mediated by NamPT enzyme, IC50 was calcula...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details
US Patent