BDBM373715 US10246444, Example 38

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CC(CCSCc1ccccc1)SCc1ccccc1

InChI Key InChIKey=INEWZJSVSGODPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373715   

TargetEpidermal growth factor receptor [L858R](Human)
Sabila Biosciences

US Patent
LigandPNGBDBM373715(US10246444, Example 38)
Affinity DataIC50: 5.50E+3nMAssay Description:KINOMEscan is based on a competition binding assay that quantitatively measures the ability of a compound to compete with an immobilized, active-site...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent