BDBM37591 3-methyl-2-oxidanylidene-N-[1-(phenylmethyl)piperidin-4-yl]-1,3-benzoxazole-6-sulfonamide::3-methyl-2-oxo-N-[1-(phenylmethyl)-4-piperidinyl]-1,3-benzoxazole-6-sulfonamide::MLS000117429::N-(1-benzyl-4-piperidyl)-2-keto-3-methyl-1,3-benzoxazole-6-sulfonamide::N-(1-benzylpiperidin-4-yl)-3-methyl-2-oxo-1,3-benzoxazole-6-sulfonamide::SMR000094377::cid_2036437

SMILES Cc1nc(-c2ccc(C[C@H](NC(=O)c3c(F)cc(N4CCOC[C@@H]4C(F)(F)F)cc3F)C(=O)O)c3cccnc23)ncc1F

InChI Key InChIKey=POXSFAGYAOVNTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37591   

TargetIntegrin alpha-4/beta-7(Human)
Gilead Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 37591BDBM37591(US11116760, Example 301)
Affinity DataEC50:  9.40nMAssay Description:The CHO cell line was cultured in T-175 sq cm Corning flasks (part 431080) at 37 deg C and 95% RH. The HTS assay began by dispensing 10 microliters o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent