BDBM436911 3-Methyl-1-(pyrimidin-4-ylmethyl)-6-[3-(trifluoromethyl)phenyl]imidazo[4,5- b]pyridin-2-one::US10617676, Example 246::US11207298, Example 246

SMILES Cn1c2ncc(cc2n(Cc2ccncn2)c1=O)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=HHZSUOMAHGCZTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436911   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436911(US10617676, Example 246 | 3-Methyl-1-(pyrimidin-4-...)
Affinity DataIC50: 349nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM436911(US10617676, Example 246 | 3-Methyl-1-(pyrimidin-4-...)
Affinity DataIC50: 349nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent