BDBM445580 US10683290, Example 73

SMILES Cc1cc(no1)[C@@H](C1CCOCC1)n1c2cc(ccc2c2ncc(cc12)C(C)(C)O)-c1c(C)nnn1C

InChI Key InChIKey=SJYKIJFHIFYUKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445580   

TargetBromodomain-containing protein 4 [1-477](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM445580(US10683290, Example 73)
Affinity DataIC50: 5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2021
Entry Details
US Patent