BDBM468321 US10806720, Compound 1001::US11230523, Compound 1001::US11648234, Compound 1001

SMILES C[C@](O)(Cn1ccc(c1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=CRUBZCCIHHRFTL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 468321   

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468321(US10806720, Compound 1001 | US11230523, Compound 1...)
Affinity DataKi:  328nMAssay Description:hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD was combin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2022
Entry Details
US Patent

TargetAndrogen receptor(Rat)
University of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM468321(US10806720, Compound 1001 | US11230523, Compound 1...)
Affinity DataKi:  328nMAssay Description:Inhibition of [3H] MIB binding to rat prostate androgen receptor LBD by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468321(US10806720, Compound 1001 | US11230523, Compound 1...)
Affinity DataKi:  328nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetAndrogen receptor [633-919](Human)
University of Tennessee Research Foundation

US Patent
LigandPNGBDBM468321(US10806720, Compound 1001 | US11230523, Compound 1...)
Affinity DataKi:  328nMAssay Description:Methods: hAR-LBD (633-919) was cloned into pGex4t.1. Large scale GST-tagged AR-LBD was prepared and purified using a GST column. Recombinant AR-LBD w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
US Patent