BDBM477358 6-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-5-chloro-N-((1S,2R)-2-(6-fluoro-2,3-::US10889555, Example 117::US11634395, Example 117

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c(n1)C(=O)N1CC2CCC(C1)O2)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477358   

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477358(6-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-5-c...)
Affinity DataIC50:  30nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477358(6-(8-oxa-3-azabicyclo[3.2.1]octane-3-carbonyl)-5-c...)
Affinity DataIC50:  30nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent