BDBM480489 US10626113, Compound F::US10899756, Compound F

SMILES COc1ccc(CNc2c3CNCCc3nc3ccc(Br)cc23)cc1Cl

InChI Key InChIKey=XNXGPHBXUMZYND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480489   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM480489(US10626113, Compound F | US10899756, Compound F)
Affinity DataIC50:  5.40nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
The Trustees of Columbia University In The City of New York

US Patent
LigandPNGBDBM480489(US10626113, Compound F | US10899756, Compound F)
Affinity DataIC50:  5.40nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent