BDBM480503 US10626113, Compound N::US10899756, Compound V
SMILES COc1ccc(cc1Cl)C(C)Nc1c2CN(CCc2nc2ccc(cc12)C#N)C(C)=O
InChI Key InChIKey=ZJEMKZMTQHUENK-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 480503
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 26.9nMAssay Description:Materials and Methods: PDE5 inhibition was assayed at BPS Bioscience (San Diego, Calif.) using BPS PDE assay kits (BPS Catalog number 60300, enzyme l...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 26.9nMAssay Description:A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...More data for this Ligand-Target Pair