BDBM484162 (S)-4-((4-isopropyl-2-methyl- 3-oxo-1-oxa-4,9- diazaspiro[5.5]undecan-9- yl)methyl)benzonitrile::US10927128, Example 83::US11649248, Example 83

SMILES CC(C)N1CC2(CCN(Cc3ccc(cc3)C#N)CC2)O[C@@H](C)C1=O

InChI Key InChIKey=MTSCAPRYQXZIGQ-INIZCTEOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 484162   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM484162((S)-4-((4-isopropyl-2-methyl- 3-oxo-1-oxa-4,9- dia...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+) -pentazocine (Perkin Elmer, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP-4 complex subunit sigma-1(Homo sapiens (Human))
Esteve Pharmaceuticals.

US Patent
LigandPNGBDBM484162((S)-4-((4-isopropyl-2-methyl- 3-oxo-1-oxa-4,9- dia...)
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human Sigma-1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent