BDBM49900 4-(2-naphthalenyl)-2-thiazolamine::4-naphthalen-2-yl-1,3-thiazol-2-amine::MLS000688336::SMR000283757::[4-(2-naphthyl)thiazol-2-yl]amine::cid_673702

SMILES Nc1nc(cs1)-c1ccc2ccccc2c1

InChI Key InChIKey=GWDNDNTTXIIXRS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 49900   

TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 49900BDBM49900(4-naphthalen-2-yl-1,3-thiazol-2-amine | 4-(2-napht...)
Affinity DataIC50: 9.16E+3nMAssay Description:Inhibition of androgen receptor transcriptional activity in human LNCaP cells after 3 days by eGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 49900BDBM49900(4-naphthalen-2-yl-1,3-thiazol-2-amine | 4-(2-napht...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of androgen receptor in human LNCaP cells assessed as inhibition of prostate-specific antigen secretion into media after 3 daysMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 49900BDBM49900(4-naphthalen-2-yl-1,3-thiazol-2-amine | 4-(2-napht...)
Affinity DataEC50:  3.55E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay