BDBM50004806 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(4-methyl-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL134545

SMILES Cc1ccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C2=O)cc1

InChI Key InChIKey=NUEVBZLYKCHOPY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50004806   

TargetD(2) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004806(CHEMBL134545 | 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]...)
Affinity DataKi:  0.0670nMAssay Description:Binding affinity towards Dopamine receptor D2 by displacing [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50004806(CHEMBL134545 | 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]...)
Affinity DataKi:  37nMAssay Description:The compound was tested in vitro for binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [125]I-LSD radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed