BDBM50005540 3-Benzoyloxy-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL172482

SMILES COC(=O)C1C2CC[C@H](C[C@@H]1OC(=O)c1ccccc1)N2

InChI Key InChIKey=AYDBLCSLKNTEJL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50005540   

TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 92nMAssay Description:Inhibition of [3H]GBR-12935 binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]cocaine binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 303nMAssay Description:Potency for the inhibition of [3H]WIN-35428 binding to the dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of [3H]mazindol binding to the dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50005540(CHEMBL172482 | 3-Benzoyloxy-8-aza-bicyclo[3.2.1]oc...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]dopamine uptake at dopamine transporter.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed