BDBM50021946 6-(4-Butyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;C4H4O4::CHEMBL285902

SMILES CCCCc1ccc(cc1)[C@@H]1CN2CCC[C@@H]2c2ccccc12

InChI Key InChIKey=CMIXRTLDLVNZTF-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50021946   

TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021946(CHEMBL285902 | 6-(4-Butyl-phenyl)-1,2,3,5,6,10b-he...)
Affinity DataKi:  30nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021946(CHEMBL285902 | 6-(4-Butyl-phenyl)-1,2,3,5,6,10b-he...)
Affinity DataKi:  110nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50021946(CHEMBL285902 | 6-(4-Butyl-phenyl)-1,2,3,5,6,10b-he...)
Affinity DataKi:  230nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed