BDBM50027045 2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-succinic acid::CHEMBL2370764

SMILES CC(C)C[C@H](N)[C@@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key InChIKey=QFAADIRHLBXJJS-XPYWIHLFSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50027045   

TargetCytosol aminopeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi:  2.00E+4nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of Aminopeptidase M from porcine kidney was determined and the Ki was reported which is ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi:  2.00E+4nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi: <2.30E+4nMAssay Description:Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi:  2.60E+4nMAssay Description:Compound was evaluated for the inhibitory activity against aminopeptidase MMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosol aminopeptidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi:  2.00E+5nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of Leucine aminopeptidase was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataKi:  2.00E+6nMAssay Description:Compound was evaluated for the inhibition of Aminopeptidase M (AP-M) and the inhibition constant was determined after preincubating the enzyme and in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50027045(2-{2-[2-(3-Amino-2-hydroxy-5-methyl-hexanoylamino)...)
Affinity DataIC50: >5.00E+5nMAssay Description:Effect of inhibitor structure on the slow binding inhibition of aminopeptidase M was determined and the Ki was reported which is = k2/k1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed