BDBM50045796 CHEMBL99939::{[2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionyl]-[2-(4-chloro-phenyl)-ethyl]-amino}-acetic acid
SMILES CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2)C(=O)N(CCc1ccc(Cl)cc1)CC(O)=O
InChI Key InChIKey=LZZPPPZINPSHEI-VQCFNYAOSA-N
Data 10 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50045796
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
University of Paris
Curated by ChEMBL
University of Paris
Curated by ChEMBL
Affinity DataKi: 6.5nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type B receptor in guinea pig brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Tested for binding affinity towards cholecystokinin type A receptor in rat pancreas by displacement of [3H]-pCCK-8 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Tested for binding affinity towards CCK-B in rat cortex by displacement of [3H]-pBC264 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Tested for binding affinity towards CCK-B in mouse brain by displacement of [3H]-pBC264 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Tested for binding affinity towards cholecystokinin type B receptor in rat cortex by displacement of [3H]-pBC264 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.06E+3nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type A receptor in guinea pig pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.13E+3nMAssay Description:Tested for inhibition of [3H]-pCCK-8 specific binding to cholecystokinin type A receptor in guinea pig pancreatic membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.23E+3nMAssay Description:Tested for binding affinity towards cholecystokinin type B receptor in mouse brain by displacement of [3H]-pBC264 radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.36E+3nMAssay Description:Tested for binding affinity towards cholecystokinin type A receptor in rat pancreas by displacement of [3H]-pCCK-8 radioligandMore data for this Ligand-Target Pair