BDBM50056763 CHEMBL168339::N-hydroxy-N-[(1S)-1-(6-methoxy-2-naphthyl)ethyl]urea

SMILES COc1ccc2cc(ccc2c1)[C@H](C)N(O)C(N)=O

InChI Key InChIKey=HMGUHSNFGLXNJV-VIFPVBQESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056763   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056763(CHEMBL168339 | N-hydroxy-N-[(1S)-1-(6-methoxy-2-na...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against 5-lipoxygenase catalysis (5-LO) in sonicated rat basophilic leukemia cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50056763(CHEMBL168339 | N-hydroxy-N-[(1S)-1-(6-methoxy-2-na...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase in Human whole blood (HWBL) stimulated with calcium ionophore (A23187) and LTB4 measured by enzyme immunoa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed