BDBM50061518 (S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimethyl-butyrylamino]-N*4*,N*4*-dimethyl-N*1*-(3,3,4,4,4-pentafluoro-1-methyl-2-oxo-butyl)-succinamide::CHEMBL134167

SMILES CC(NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@@H](NC(=O)CC(C)(C)C)C(C)(C)C)C(=O)C(F)(F)C(F)(F)F

InChI Key InChIKey=OLFIHCKGMDLZFK-XBUJOUKBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50061518   

TargetGenome polyprotein(Human rhinovirus B)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  110nMAssay Description:Micro molar potency of the compound to inhibit human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  1.40E+4nMAssay Description:Activity against serine protease bovine pancreatic Alpha-Chymotrypsinogen (BPC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50: >3.00E+5nMAssay Description:Activity against serine protease human liver Cathepsin B (cat-B )More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50: >3.00E+5nMAssay Description:Binding affinity for human leukocyte elastase(HLE) serine proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
Boehringer Ingelheim

Curated by ChEMBL
LigandPNGBDBM50061518((S)-2-[(S)-2-(3,3-Dimethyl-butyrylamino)-3,3-dimet...)
Affinity DataIC50:  3.30E+4nMAssay Description:Activity against serine protease porcine pancreatic elastase (PPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed