BDBM50065302 6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL87208

SMILES Fc1ccc2\C(=C\c3ccc[nH]3)C(=O)Nc2c1

InChI Key InChIKey=JFVLMRYDPQMRFA-XFFZJAGNSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065302   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50065302(6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50065302(6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50065302(6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Sugen

Curated by ChEMBL
LigandPNGBDBM50065302(6-Fluoro-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1...)
Affinity DataIC50:  2.80E+3nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed