BDBM50066879 CHEMBL3401663

SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cccc(n1)C1CCN(CC1)c1ccc(cn1)C#N)C(C3)C2

InChI Key InChIKey=NENNJMIHZPOYNW-XUXRVEEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50066879   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066879(CHEMBL3401663)
Affinity DataIC50:  18nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50066879(CHEMBL3401663)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human 11beta-HSD1 using microsomal fraction and NADPH assessed as conversion of cortisone to cortisol by biochemical enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed