BDBM50084487 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5-methoxy-3,4-dihydro-2H-isoquinolin-1-one (2HCL .3/2H2O)::CHEMBL96799

SMILES COc1cccc2C(=O)N(CCN3CCN(CC3)c3ccc(Cl)cc3)CCc12

InChI Key InChIKey=RSEPGIMWDIKONM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084487   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084487(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5...)
Affinity DataKi:  42nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084487(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5...)
Affinity DataKi:  451nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine receptor 1A receptor in rat hippocampal membranes by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084487(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-5...)
Affinity DataKi:  3.17E+3nMAssay Description:In vitro binding affinity towards human Dopamine receptor D2L, using [3H]-spiroperidol radioligand in Sf9 baculovirus expression.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed