BDBM50084489 2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-7-methoxy-3,4-dihydro-2H-isoquinolin-1-one::CHEMBL330470

SMILES COc1ccc2CCN(CCN3CCN(CC3)c3ccc(Cl)cc3)C(=O)c2c1

InChI Key InChIKey=FLUICVJCLNQVDT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50084489   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084489(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-7...)
Affinity DataKi:  11nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine receptor 1A receptor in rat hippocampal membranes by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084489(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-7...)
Affinity DataKi:  141nMAssay Description:In vitro binding affinity at human Dopamine receptor D4.4 by [3H]-YM-09151-2 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universitá

Curated by ChEMBL
LigandPNGBDBM50084489(2-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-ethyl}-7...)
Affinity DataKi:  3.96E+3nMAssay Description:In vitro binding affinity at human Dopamine receptor D2 (long) by [3H]-spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed