BDBM50099143 2-{4-[2-(4-Methyl-piperazin-1-yl)-phenylsulfanyl]-3-trifluoromethyl-phenyl}-cyclopropanecarboxylic acid [3-(2-oxo-pyrrolidin-1-yl)-propyl]-amide::CHEMBL176415
SMILES CN1CCN(CC1)c1ccccc1Sc1ccc(cc1C(F)(F)F)C1CC1C(=O)NCCCN1CCCC1=O
InChI Key InChIKey=HPSCLHCEPQQJNB-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50099143
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:50% inhibition of JY-8 cell adhesion to ICAM-1 via leukocyte function-associated antigen-1 (LFA-1) with 50% FBSMore data for this Ligand-Target Pair