BDBM50099143 2-{4-[2-(4-Methyl-piperazin-1-yl)-phenylsulfanyl]-3-trifluoromethyl-phenyl}-cyclopropanecarboxylic acid [3-(2-oxo-pyrrolidin-1-yl)-propyl]-amide::CHEMBL176415

SMILES CN1CCN(CC1)c1ccccc1Sc1ccc(cc1C(F)(F)F)C1CC1C(=O)NCCCN1CCCC1=O

InChI Key InChIKey=HPSCLHCEPQQJNB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099143   

TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099143(2-{4-[2-(4-Methyl-piperazin-1-yl)-phenylsulfanyl]-...)
Affinity DataIC50:  200nMAssay Description:50% inhibition of JY-8 cell adhesion to ICAM-1 via leukocyte function-associated antigen-1 (LFA-1) with 50% FBSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed