BDBM50099968 CHEMBL31653::N*4*-(2-Benzyl-1H-benzoimidazol-5-yl)-pyrido[3,4-d]pyrimidine-4,6-diamine

SMILES Nc1cc2c(Nc3ccc4nc(Cc5ccccc5)[nH]c4c3)ncnc2cn1

InChI Key InChIKey=HRXDZJIGRRYXTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099968   

TargetReceptor tyrosine-protein kinase erbB-2(Rattus norvegicus)
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099968(CHEMBL31653 | N*4*-(2-Benzyl-1H-benzoimidazol-5-yl...)
Affinity DataIC50:  49nMAssay Description:Inhibition of rat Receptor protein-tyrosine kinase erbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Research Biomet. Glaxo Wellcome Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50099968(CHEMBL31653 | N*4*-(2-Benzyl-1H-benzoimidazol-5-yl...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of c-erbB-2 overexpressing HB4a cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed