BDBM50105220 4-[4-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phenoxy]-thieno[2,3-c]pyridine-2-carboxylic acid methylamide::CHEMBL116454

SMILES CNC(=O)c1cc2c(Oc3ccc(cc3)-c3noc(n3)C(F)(F)F)cncc2s1

InChI Key InChIKey=LBYIVNYUBVIWHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105220   

TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105220(4-[4-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phe...)
Affinity DataIC50:  28nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105220(4-[4-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phe...)
Affinity DataIC50:  22nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105220(4-[4-(5-Trifluoromethyl-[1,2,4]oxadiazol-3-yl)-phe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed