BDBM50134722 5alpha-androst-16-en-3alpha-ol::CHEMBL142348

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@]34C)[C@@H]1CC=C2

InChI Key InChIKey=KRVXMNNRSSQZJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134722   

TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134722BDBM50134722(5alpha-androst-16-en-3alpha-ol | CHEMBL142348)
Affinity DataIC50: 250nMAssay Description:Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetNuclear receptor subfamily 1 group I member 3(Mouse)
University of Kuopio

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134722BDBM50134722(5alpha-androst-16-en-3alpha-ol | CHEMBL142348)
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration against mammalian m-constitutive androstane receptor (mCAR) activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134722BDBM50134722(5alpha-androst-16-en-3alpha-ol | CHEMBL142348)
Affinity DataIC50: 339nMAssay Description:Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed