BDBM50135571 3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL133070

SMILES COC(=O)C1C2CCC(CC1c1ccc(C(C)=O)c(c1)C(C)=O)N2C

InChI Key InChIKey=CFMJSXBSNWAVPU-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50135571   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  704nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  704nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hDAT in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [125I]RT155 to hNET in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [H]norepinephrine to NE receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50135571(3-(3,4-Diacetyl-phenyl)-8-methyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  330nMAssay Description:Inhibition of [3H]5-HT uptake in HEK cells expressing human SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed