BDBM50136206 3-[(4-Chloro-phenoxy)-(4-fluoro-phenyl)-methyl]-piperidine::CHEMBL153735

SMILES Fc1ccc(cc1)C(Oc1ccc(Cl)cc1)C1CCCNC1

InChI Key InChIKey=AUZWJAMWJZUPHQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50136206   

TargetSodium-dependent serotonin transporter(Rat)
Faes Farma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136206BDBM50136206(3-[(4-Chloro-phenoxy)-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataKi:  13.9nMAssay Description:Binding affinity to the serotonin transporter (SERT) measured by displacement of [3H]paroxetine in male wistar ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Faes Farma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136206BDBM50136206(3-[(4-Chloro-phenoxy)-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Faes Farma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50136206BDBM50136206(3-[(4-Chloro-phenoxy)-(4-fluoro-phenyl)-methyl]-pi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed