BDBM50143827 (E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-4,5,6,7-tetrahydro-benzofuran-2-yl]-acrylic acid::CHEMBL294346

SMILES COc1cc2c(cc1C1CCCc3oc(\C=C\C(O)=O)cc13)C(C)(C)CCC2(C)C

InChI Key InChIKey=RJQKKTLAFODUMP-MDZDMXLPSA-N

Data  2 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50143827   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataKi:  20nMAssay Description:Binding affinity for retinoid X receptor alpha (RXRalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acidMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration for retinoic acid receptor alpha induced lipogenesis in C3H10T1/2 clone 8 fibroblast cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataEC50:  48nMAssay Description:Effective concentration for Retinoid X receptor alpha activity in CV-1 cells; Partial agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration for Retinoic acid receptor alpha activity in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50143827((E)-3-[4-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,8-te...)
Affinity DataEC50:  123nMAssay Description:Effective concentration for lipogenesis induced by retinoid X receptor alpha in C3H10T1/2 clone 8 fibroblast cells; Partial agonistMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed