BDBM50165277 1-[4-(6-Amino-9-pent-4-ynyl-9H-purin-8-ylsulfanyl)-phenyl]-ethanone::CHEMBL363860

SMILES CC(=O)c1ccc(Sc2nc3c(N)ncnc3n2CCCC#C)cc1

InChI Key InChIKey=YDINIXPBRUCUAZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165277   

TargetHeat shock protein HSP 90-alpha(Mus musculus)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165277(1-[4-(6-Amino-9-pent-4-ynyl-9H-purin-8-ylsulfanyl)...)
Affinity DataEC50:  2.70E+3nMAssay Description:Displacement of 5 nM GM-BODIPY from mouse heat shock protein HSP90-alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50165277(1-[4-(6-Amino-9-pent-4-ynyl-9H-purin-8-ylsulfanyl)...)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of Hsp90 protein as degradation of HER2 kinase in SKBr3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed