BDBM50185171 CHEMBL379108::N-(cyclohexylmethyl)-3-(5-(4-(piperidin-1-yl)piperidin-1-yl)-1H-benzo[d]imidazol-2-yl)-1H-indazol-5-amine

SMILES C(Nc1ccc2[nH]nc(-c3nc4ccc(cc4[nH]3)N3CCC(CC3)N3CCCCC3)c2c1)C1CCCCC1

InChI Key InChIKey=HMKZBWZSRGIVPM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185171   

TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  44nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed