BDBM50186691 (S)-tert-butyl 4-(2,2-diphenylacetamido)-5-((S)-1-((S,E)-5-methyl-1-(methylsulfonyl)hex-1-en-3-ylamino)-1-oxopropan-2-ylamino)-5-oxopentanoate::CHEMBL376815

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)C(c1ccccc1)c1ccccc1)\C=C\S(C)(=O)=O

InChI Key InChIKey=ILPPYSQNXLYJCB-BHLSWWIFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50186691   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186691((S)-tert-butyl 4-(2,2-diphenylacetamido)-5-((S)-1-...)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186691((S)-tert-butyl 4-(2,2-diphenylacetamido)-5-((S)-1-...)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186691((S)-tert-butyl 4-(2,2-diphenylacetamido)-5-((S)-1-...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed