BDBM50187394 CHEMBL207220::N-(3-{4-[4-(cyclohexylmethanesulfonyl-methyl-amino)-butyl]-piperazin-1-yl}-phenyl)-acetamide

SMILES CN(CCCCN1CCN(CC1)c1cccc(NC(C)=O)c1)S(=O)(=O)CC1CCCCC1

InChI Key InChIKey=TYHOTEDHXUXEPY-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50187394   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187394(CHEMBL207220 | N-(3-{4-[4-(cyclohexylmethanesulfon...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187394(CHEMBL207220 | N-(3-{4-[4-(cyclohexylmethanesulfon...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of hERG potassium channel in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Predix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50187394(CHEMBL207220 | N-(3-{4-[4-(cyclohexylmethanesulfon...)
Affinity DataEC50:  3.60nMAssay Description:Activity against 5HT1A receptor by Gi-[35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed