BDBM50194562 CHEMBL375222::N'-(8-fluoro-2-phenyl-3-piperazin-1-ylmethyl-quinoline-4-carbonyl)-N-phenyl-hydrazinecarboxylic acid methyl ester

SMILES COC(=O)N(NC(=O)c1c(CN2CCNCC2)c(nc2c(F)cccc12)-c1ccccc1)c1ccccc1

InChI Key InChIKey=OXGFBXMELSULAL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194562   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194562(CHEMBL375222 | N'-(8-fluoro-2-phenyl-3-piperazin-1...)
Affinity DataKi:  8.20E+3nMAssay Description:Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50194562(CHEMBL375222 | N'-(8-fluoro-2-phenyl-3-piperazin-1...)
Affinity DataIC50:  37nMAssay Description:Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed