BDBM50201054 (1R,6S)-8-(6-chloro-5-methyl-pyridin-3-yl)-3,8-diaza-bicyclo[4.2.0]octane::CHEMBL218544
SMILES Cc1cc(cnc1Cl)N1C[C@@H]2CCNC[C@H]12
InChI Key InChIKey=UXNFBEZSLURUHM-ONGXEEELSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50201054
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 76.1nMAssay Description:Agonist activity at human alpha4beta2 ACHR expressed in HEK293 cells assessed as change in intracellular calcium concentration by FLIPRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Burnham Institute For Medical Research
Curated by ChEMBL
Burnham Institute For Medical Research
Curated by ChEMBL
Affinity DataEC50: 1.91E+3nMAssay Description:Agonist activity against human alpha3beta4 nAChRMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
Burnham Institute For Medical Research
Curated by ChEMBL
Burnham Institute For Medical Research
Curated by ChEMBL
Affinity DataEC50: 75.9nMAssay Description:Agonist activity against human alpha4beta2 nAChRMore data for this Ligand-Target Pair