BDBM50208093 CHEMBL3953289::US9708270, 25

SMILES OC(=O)CC1CCC2(CC1)CCN(CC2)c1cc(SC(F)(F)F)cc(c1)C#N

InChI Key InChIKey=DXIACLRPBPXBLP-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208093   

TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  44nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  480nMAssay Description:Agonist activity at ARMS2-PK2 -tagged human GPR120 short isoform expressed in CHOK1 cells assessed as induction of beta-arrestin2 recruitment after 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  140nMAssay Description:Agonist activity at mouse GPR120 expressed in U2OS cells assessed as induction of beta-arrestin2 recruitment after 90 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  1.15E+3nMAssay Description:On the day before the measurement day, CHO cells expressing human GPR120 were plated at 10000 cells per well in a 384-well black plate (#3702, Cornin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFree fatty acid receptor 4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  360nMAssay Description:Agonist activity at human GPR120 short isoform expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 4(Mus musculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50:  44nMAssay Description:Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50208093(CHEMBL3953289 | US9708270, 25)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of IP1 accumulation after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed