BDBM50213944 CHEMBL399096::isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)OCC(C)C)C(=O)NO

InChI Key InChIKey=AGMWQNDXCWDRDZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50213944   

TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  3.41E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  3.41E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  960nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  960nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
University Of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(CHEMBL399096 | isobutyl 3-((4-(but-2-ynyloxy)pheny...)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed